1- Resistance and Stability of a New Method for Bonding Biological Materials Using Sutures and Biological Adhesives
Title: Resistance and Stability of a New Method for Bonding Biological Materials Using Sutures and Biological Adhesives
Authors: J M García Paéz 1, A Carrera Sanmartín, E Jorge Herrero, I Millan, A Cordon, A Rocha, M A Maestro, G Téllez, J L Castillo-Olivares
J Biomater Appl. 2005 Jan;19(3):215-36.
doi: 10.1177/0885328205046633.
Abstract: The valve leaflets of cardiac bioprostheses are secured and shaped by sutures which, given their high degree of resistance and poor elasticity, have been implicated in the generation of stresses within the leaflets, contributing to the failure of the bioprostheses. Bioadhesives are bonding materials that have begun to be utilized in surgery, although there is a lack of experience in their use with inert tissues or bioprostheses.
Tensile testing is performed until rupture in samples of calf pericardium, a biomaterial employed in the manufacture of bioprosthetic heart valve leaflets.
One hundred and thirty-two trials are carried out in three types of samples: intact or control tissue (n¼12); samples transected and glued in an overlapping manner with a cyanoacrylate (n¼60), and samples transected, sewn with commercially available suture material and reinforced at the suture holes with the same cyanoacrylate (n¼60). Seven days after their preparation, 12 samples
from each group, including the controls, are subjected to tensile testing until rupture, and the findings are compared.
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